Alzheimer's Disease and Frontotemporal Dementias

A Review with Particular Reference to Pin1 Protein

 

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Compiled by: Julian Thorpe

 

Literature A - K

 
N.B. Free Medical Journals online now at: http://www.freemedicaljournals.com/
(These journals include: Neurology, Neurobiology of Disease, Journal of Neurochemistry, Alzheimer's Disease Review) 
A

Go to: A ; B ; C ; D ; E ; F ; G ; H ; I ; J ; K ; Literature L-Z


Abdul, HM, Wenk, GL, Gramling, M, Hauss-Wegrzyniak, B, Butterfield, DA (2004)
APP and PS-1 mutations induce brain oxidative stress independent of dietary cholesterol: implications for Alzheimer's disease. NEUROSCIENCE LETTERS 368: 148-150

Abe, K and Saito, H (2000) Amyloid beta neurotoxicity not mediated by the mitogen-activated protein kinase cascade in cultured rat hippocampal and cortical neurons. NEUROSCIENCE LETTERS 292: 1-4

Abe, Y, Kouyama, K, Tomita, T, Tomita, Y, Ban, N, Nawa, M, Matsuoka, M, Niikura, T, Aiso, S, Kita, Y, Iwatsubo, T, Nishimoto, I (2003) Analysis of neurons created from wild-type and Alzheimer's mutation knock-in embryonic stem cells by a highly efficient differentiation protocol. JOURNAL OF NEUROSCIENCE 23: 8513-8525

Abraha, A, Ghoshal, N, Gamblin, TC, Cryns, V, Berry, RW, Kuret, J and Binder, LI (2000) C-terminal inhibition of tau assembly in vitro and in Alzheimer's disease. JOURNAL OF CELL SCIENCE 113: 3737-3745

Abraham, C. R.; Selkoe, D. J.; Potter, H. (1988) Immunochemical identification of the serine protease inhibitor alpha-1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease. Cell 52: 487-501.

Abraham, R, Hamshere, M, Myers, A, Kwon, J, Spurlock, G, Thomas, H, Turic, D, Marshall, H, De-Vrieze, FW, Compton, D, Hoogendoom, B, Liolitsa, D, Lovestone, S, Hardy, J, Goate, A, O'Donovan, M, Williams, J, Owen, MJ, Jones, L (2001) Insulin degrading enzyme is not associated with late-onset Alzheimer's disease. AMERICAN JOURNAL OF HUMAN GENETICS 69: 2236

Abraham, R, Myers, A, Wavrant-DeVrieze, F, Hamshere, ML, Thomas, HV, Marshall, H, Compton, D, Spurlock, G, Turic, D, Hoogendoorn, B, Kwon, KM, Petersen, RC, Tangalos, E, Norton, J, Morris, JC, Bullock, R, Liolitsa, S, Lovestone, S, Hardy, J, Goate, A, O'Donovan, M, Williams, J, Owen, MJ, Jones, L (2001) Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease. HUMAN GENETICS 109: 646-652

Abrahamsen, H, Gao, TY, Jennings, P, Newton, A (2005) Pin1 regulates the activation-induced downregulation of PKC  beta II. FASEB JOURNAL 19:  A272

Abramova, NA, Cassarino, DS, Khan, SM, Painter, TW, Bennett, JP (2002) Inhibition by R(+) or S(-) pramipexole of caspase activation and cell death induced by methylpyridinium ion or beta amyloid peptide in SH-SY5Y neuroblastoma. JOURNAL OF NEUROSCIENCE RESEARCH 67: 494-500

Acharya, A, Xu, XJ, Husain-Ponnampalam, RD, Hoffmann-Benning, S, Kuo, MH (2005) Production of constitutively acetylated recombinant p53 from yeast and Escherichia coli by tethered catalysis. PROTEIN EXPRESSION AND PURIFICATION  41: 417-425

Ackerley, S, Thornhill, P, Grierson, AJ, Brownlees, J, Anderton, BH, Leigh, PN, Shaw, CE, Miller, CCJ (2003) Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments. JOURNAL OF CELL BIOLOGY 161: 489-495

Adamec, E, Chang, HT, Stopa, EG, Hedreen, JC, Vonsattel, JP (2001) Tau protein expression in frontotemporal dementias. NEUROSCIENCE LETTERS 315: 21-24

Adamec, E, Murrell, JR, Takao, M, Hobbs, W, Nixon, RA, Ghetti, B, Vonsattel, JP (2002) P301L tauopathy: confocal immunofluorescence study of perinuclear aggregation of the mutated protein. JOURNAL OF THE NEUROLOGICAL SCIENCES 200: 85-93

Adlard, PA, Vickers, JC (2002) Morphologically distinct plaque types differentially affect dendritic structure and organisation in the early and late stages of Alzheimer's disease. ACTA NEUROPATHOLOGICA 103: 377-383

Agius, LM (2003) beta-amyloidosis as an index of activity of the Alzheimer process rather than as a primary mechanism of neuronal injury in organic dementia. MEDICAL HYPOTHESES 60: 880-885  

Agorogiannis, EI, Agorogiannis, GI, Papadimitriou, A, Hadjigeorgiou, GM (2004) Protein misfolding in neurodegenerative diseases. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 30: 215-224

Aguzzi, A, Haass, C (2003) Games played by rogue proteins in prion disorders and Alzheimer's disease. SCIENCE 302: 814-818

Ahlijanian MK; Barrezueta NX; Williams RD; Jakowski A; Kowsz KP; McCarthy S; Coskran T; Carlo A; Seymour PA; Burkhardt JE;Nelson RB; McNeish JD (2000). Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5. Proc Natl Acad Sci USA 97: 2910-2915

Ahmed, ARH, Ho, PKY and Jones, RW (2000) Increased markers of oxidative stress in patients with Alzheimer's disease. ALZHEIMERS REPORTS 3: 269-273

Ait-Ghezala, G, Abdullah, L, Crescentini, R, Crawford, F, Town, T, Singh, S, Richards, D, Duara, R, Mullan, M (2002) Confirmation of association between D10S583 and Alzheimer's disease in a case-control sample. NEUROSCIENCE LETTERS 325: 87-90

Akiyama H, Shin R-W, Uchida C, Kitamtoto T, Uchida T (2005) Pin1 promotes production of Alzheimer's amyloid b from b-cleaved amyloid precursor protein.  Biochemical and Biophysical Research Communications 336: 521-529

Aksenov, MY, Aksenova, MV, Butterfield, DA, Geddes, JW and Markesbery, WR (2001) Protein oxidation in the brain in Alzheimer's disease. NEUROSCIENCE 103: 373-383

Albers, DS and Augood, SJ (2001) New insights into progressive supranuclear palsy. TRENDS IN NEUROSCIENCES 24: 347-352

Albers, DS, Beal, MF (2002) Mitochondrial dysfunction in progressive supranuclear palsy. NEUROCHEMISTRY INTERNATIONAL 40: 559-564

Albers, DS, Swerdlow, RH, Manfredi, G, Gajewski, C, Yang, LC, Parker, WD, Beal, MF (2001) Further evidence for mitochondrial dysfunction in progressive supranuclear palsy. EXPERIMENTAL NEUROLOGY 168: 196-198

Albert A, Lavoie S, Vincent M (1999) A hyperphosphorylated form of RNA polymerase II is the major interphase antigen of the phosphoprotein antibody MPM-2 and interacts with the peptidyl-prolyl isomerase Pin1. J Cell Science 112: 2493-2500

Albert, AL, Lavoie, SB, Vincent, M (2004) Multisite phosphorylation of Pin1-associated mitotic phosphoproteins revealed by monoclonal antibodies MPM-2 and CC-3. BMC CELL BIOLOGY 5: 10-22

Aletta_Jm, Shelanski_Ml, Greene_La. (1989) Phosphorylation Of The Peripherin 58-Kda Neuronal Intermediate Filament Protein - Regulation By Nerve Growth-Factor And Other Agents. JOURNAL OF BIOLOGICAL CHEMISTRY, Vol.264, No.8, pp.4619- 4627

Aliev, G, Smith, MA, Seyidova, D, Neal, ML, Lamb, BT, Nunomura, A, Gasimov, EK, Vinters, HV, Perry, G, LaManna, JC, Friedland, RP (2002) The role of oxidative stress in the pathophysiology of cerebrovascular lesions in Alzheimer's disease. BRAIN PATHOLOGY 12: 21-35

Allen, B, Ingram, E, Takao, M, Smith, MJ, Jakes, R, Virdee, K, Yoshida, H, Holzer, M, Craxton, M, Emson, PC, Atzori, C, Migheli, A, Crowther, RA, Ghetti, B, Spillantini, MG, Goedert, M (2002) Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein . JOURNAL OF NEUROSCIENCE 22: 9340-9351

Allen, JW, Eldadah, BA, Huang, XL, Knoblach, SM and Faden, AI (2001) Multiple caspases are involved in beta-amyloid-induced neuronal apoptosis. JOURNAL OF NEUROSCIENCE RESEARCH 65: 45-53

Allsop, D, Twyman, LJ, Davies, Y, Moore, S, York, A, Swanson, L, Soutar, I (2001) Modulation of beta-amyloid production and fibrillization. NEURONAL SIGNAL TRANSDUCTION AND ALZHEIMER'S DISEASE 67: 1-14

Almeida, OP, Hulse, GK, Lawrence, D, Flicker, L (2002) Smoking as a risk factor for Alzheimer's disease: contrasting evidence from a systematic review of case-control and cohort studies. ADDICTION 97: 15-28

Alonso, AD, Zaidi, T, Novak, M, Grundke-Iqbal, I and Iqbal, K (2001) Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98: 6923-6928

Alvarez, A, Munoz, JP and Maccioni, RB (2001) A cdk5-p35 stable complex is involved in the beta-amyloid-induced deregulation of cdk5 activity in hippocampal neurons. EXPERIMENTAL CELL RESEARCH 264: 266-274

Alvarez, A, Toro, R, Caceres, A and Maccioni, RB (2000) Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloid-induced neuronal death. FEBS LETTERS 459: 421-426

Alvarez, G, Munoz-Montano, JR, Satrustegui, J, Avila, J, Bogonez, E, Diaz-Nido, J (2002) Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease. BIPOLAR DISORDERS 4: 153-165

An, WL, Bjorkdahl, C, Liu, R, Cowburn, RF, Winblad, B, Pei, JJ (2005) Mechanism of zinc-induced phosphorylation of p70 S6 kinase and glycogen synthase kinase 3 beta in SH-SY5Y neuroblastoma cells. JOURNAL OF NEUROCHEMISTRY 92: 1104-1115

An, WL, Cowburn, RF, Li, L, Braak, H, Alafuzoff, I, Iqbal, K, Grundke-Iqbal, IG, Winblad, B, Pei, JJ (2003) Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease. AMERICAN JOURNAL OF PATHOLOGY 163: 591-607

Anandatheerthavarada, HK, Biswas, G, Robin, MA, Avadhani, NG (2003) Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells. JOURNAL OF CELL BIOLOGY 161: 41-54

Anderson, AJ, Stoltzner, S, Lai, F, Su, J and Nixon, RA (2000) Morphological and biochemical assessment of DNA damage and apoptosis in Down syndrome and Alzheimer disease, and effect of postmortem tissue archival on TUNEL. NEUROBIOLOGY OF AGING 21: 511-524

Anderson, AJ, Su, JH and Cotman, CW (1996) DNA damage and apoptosis in Alzheimer's disease: Colocalization with c-Jun immunoreactivity, relationship to brain area, and effect of postmortem delay. JOURNAL OF NEUROSCIENCE 16: 1710-1719

Anderson, I, Adinolfi, C, Doctrow, S, Huffman, K, Joy, KA, Malfroy, B, Soden, P, Rupniak, HT, Barnes, JC (2001) Oxidative signalling and inflammatory pathways in Alzheimer's disease. NEURONAL SIGNAL TRANSDUCTION AND ALZHEIMER'S DISEASE 67: 141-149

Anderson, SJ, Barker, PE, Hadfield, MG (2002) Cytonectin expression in Alzheimer disease. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 61: 230-236

Andersson, K, Olofsson, A, Nielsen, EH, Svehag, SE, Lundgren, E (2002) Only amyloidogenic intermediates of transthyretin induce apoptosis. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 294: 309-314

Anderton, BH, Betts, J, Blackstock, WP, Brion, JP, Chapman, S, Connell, J, Dayanandan, R, Gallo, JM, Gibb, G, Hanger, DP, Hutton, M, Kardalinou, E, Leroy, K, Lovestone, S, Mack, T, Reynolds, CH, Van Slegtenhorst, M (2001) Sites of phosphorylation in tau and factors affecting their regulation. NEURONAL SIGNAL TRANSDUCTION AND ALZHEIMER'S DISEASE 67: 73-80

Anderton, BH, Dayanandan, R, Killick, R and Lovestone, S (2000) Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer's disease? MOLECULAR MEDICINE TODAY 6: 54-59

Andorfer, C, Acker, CM, Kress, Y, Hof, PR, Duff, K, Davies, P (2005) Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms. JOURNAL OF NEUROSCIENCE 25: 5446-5454

Andorfer, CA and Davies, P (2000) PKA phosphorylations on tau: Developmental studies in the mouse. DEVELOPMENTAL NEUROSCIENCE 22: 303-309

Andorfer, C, Kress, Y, Espinoza, M, de Silva, R, Tucker, KL, Barde, YA, Duff, K, Davies, P (2003) Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms. JOURNAL OF NEUROCHEMISTRY 86: 582-590  

Andreasen, N, Blennow, K (2005) CSF biomarkers for mild cognitive impairment and early Alzheimer's disease. CLINICAL NEUROLOGY AND NEUROSURGERY 107: 165-173

Angelastro_JM, Ho_CL, Frappier_T, Liem_RKH, Greene_LA. (1998) Peripherin is tyrosine-phosphorylated at its carboxyl-terminal tyrosine. JOURNAL OF NEUROCHEMISTRY,Vol.70, No.2, pp.540-549

Angelo, M, Plattner, F, Irvine, EE, Giese, KP (2003) Improved reversal learning and altered fear conditioning in transgenic mice with regionally restricted p25 expression. EUROPEAN JOURNAL OF NEUROSCIENCE 18: 423-431

Annaert, W, Cupers, P, Saftig, P, De Strooper, B (2000) Presenilin function in APP processing. MOLECULAR BASIS OF DEMENTIA. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 920: 158-164

Apelt, J, Mehlhorn, G, Hollborn, M and Schliebs, R (2000) Induction of cytokines in glial cells surrounding cortical beta-amyloid plaques in transgenic TG2576 mice with Alzheimer pathology. EUROPEAN JOURNAL OF NEUROSCIENCE 12: 211

Apelt, J and Schliebs, R (2001) beta-Amyloid-induced glial expression of both pro- and anti-inflammatory cytokines in cerebral cortex of aged transgenic Tg2576 mice with Alzheimer plaque pathology. BRAIN RESEARCH 894: 21-30

Arai, H, Ishiguro, K, Ohno, H, Moriyama, M, Itoh, N, Okamura, N, Matsui, T, Morikawa, Y, Horikawa, E, Kohno, H, Sasaki, H, Imahori, K (2000) CSF phosphorylated tau protein and mild cognitive impairment: a prospective study. EXPERIMENTAL NEUROLOGY 166: 201-203

Arai, T, Ikeda, K, Akiyama, H, Tsuchiya, K, Yagishita, S, Takamatsu, J (2001) Intracellular processing of aggregated tan differs between corticobasal degeneration and progressive supranuclear palsy. NEUROREPORT 12: 935-938

Arai, T, Ikeda, K, Akiyama, H, Shikamoto, Y, Tsuchiya, K, Yagishita, S, Beach, T, Rogers, J, Schwab, C, McGeer, PL (2001) Distinct isoforms of tau aggregated in neurons and glial cells in brains of patients with Pick's disease, corticobasal degeneration and progressive supranuclear palsy. ACTA NEUROPATHOLOGICA 101: 167-173

Arai, T, Ikeda, K, Akiyama, H, Tsuchiya, K, Iritani, S, Ishiguro, K, Yagishita, S, Oda, T, Odawara, T, Iseki, E (2003) Different immunoreactivities of the microtubule-binding region of tau and its molecular basis in brains from patients with Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration. ACTA NEUROPATHOLOGICA 105: 489-498

Arai, T, Nonaka, T, Hasegawa, M, Akiyama, H, Yoshida, M, Hashizume, Y, Tsuchiya, K, Oda, T, Ikeda, K (2003) Neuronal and glial inclusions in frontotemporal dementia with or without motor neuron disease are immunopositive for p62. NEUROSCIENCE LETTERS 342: 41-44

Arai, Y, Yamazaki, M,  Mori, O, Muramatsu, H, Asano, G and Katayama, Y (2001) alpha-Synuclein-positive structures in cases with sporadic  Alzheimer's disease: morphology and its relationship to tau aggregation. BRAIN RESEARCH 888: 287-296

Araki, W, Yuasa, K, Takeda, S, Shirotani, K, Takahashi, K, Tabira, T (2000) Overexpression of presenilin-2 enhances apoptotic death of cultured cortical neurons. MOLECULAR BASIS OF DEMENTIA. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 920: 241-244

Araki, W, Yuasa, K, Takeda, S, Takeda, K, Shirotani, K, Takahashi, K, Tabira, T (2001) Pro-apoptotic effect of presenilin 2 (PS2) overexpression is associated with down-regulation of Bcl-2 in cultured neurons. JOURNAL OF NEUROCHEMISTRY 79: 1161-1168

Arango, D, Cruts, M, Torres, O, Backhovens, H, Serrano, ML, Villareal, E, Montanes, P, Matallana, D, Cano, C, Van Broeckhoven, C, Jacquier, M (2001) Systematic genetic study of Alzheimer disease in Latin America: Mutation frequencies of the amyloid beta precursor protein and presenilin genes in Colombia. AMERICAN JOURNAL OF MEDICAL GENETICS 103: 138-143

Ardley, HC, Scott, GB, Rose, SA, Tan, NGS, Markham, AF, Robinson, PA (2003) Inhibition of proteasomal activity causes inclusion formation in neuronal and non-neuronal cells overexpressing Parkin. MOLECULAR BIOLOGY OF THE CELL 14: 4541-4556

Arendash, GW, Gordon, MN, Diamond, DM, Austin, LA, Hatcher, JM, Jantzen, P, Dicarlo, G, Wilcock, D, Morgan, D (2001) Behavioral assessment of Alzheimer's transgenic mice following long-term A beta vaccination: Task specificity and correlations between A beta deposition and spatial memory. DNA AND CELL BIOLOGY 20: 737-744

Arendash, GW, King, DL, Gordon, MN, Morgan, D, Hatcher, JM, Hope, CE and Diamond, DM (2001) Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes. BRAIN RESEARCH 891: 42-53

Arendt, T (2000) Alzheimer's disease as a loss of differentiation control in a subset of neurons that retain immature features in the adult brain. NEUROBIOLOGY OF AGING 21: 783-796

Arendt, T (2001) Alzheimer's disease as a disorder of mechanisms underlying structural brain self-organization. NEUROSCIENCE 102: 723-765

Arendt, T (2002) Dysregulation of neuronal differentiation and cell cycle control in Alzheimer's disease
JOURNAL OF NEURAL TRANSMISSION-SUPPLEMENT 62: 77-85

Arendt, T (2003) Synaptic plasticity and cell cycle activation in neurons are alternative effector pathways: the 'Dr. Jekyll and Mr. Hyde concept' of Alzheimer's disease or the yin and yang of neuroplasticity. PROGRESS IN NEUROBIOLOGY 71: 83-248  

Arendt, T (2004) Neurodegeneration and plasticity. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE 22: 507-514

Arendt, T, Holzer, M and Bruckner, MK (1998) Neuronal expression of cell-cycle-markers in Alzheimer's disease. EUROPEAN JOURNAL OF NEUROSCIENCE 10: 3217

Arendt_T, Holzer_M, Fruth_R, Bruckner_MK, Gartner_U. (1998) Phosphorylation of tau, A beta-formation, and apoptosis after in vivo inhibition of PP-1 and PP-2A. NEUROBIOLOGY OF AGING, Vol.19, No.1, pp.3-13

Arendt, T, Holzer, M and Gartner, U (1998) Neuronal expression of cycline dependent kinase inhibitors of the INK4 family in Alzheimer's disease. JOURNAL OF NEURAL TRANSMISSION 105: 949-960

Arendt, T, Holzer, M, Gartner, U and Bruckner, MK (1998) Aberrancies in signal transduction and cell cycle related events in Alzheimer's disease. JOURNAL OF NEURAL TRANSMISSION SU54: 147-158

Arendt, T, Holzer, M, Stobe, A, Gartner, U, Luth, HJ, Bruckner, MK, Ueberham, U (2000) Activated mitogenic signaling induces a process of dedifferentiation in Alzheimer's disease that eventually results in cell death. MOLECULAR BASIS OF DEMENTIA. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES 920: 249-255

Arendt, T, Holzer, M, Stobe, A, Ueberham, U, Gartner, U and Bruckner, MK (2000) Cell cycle regulatory factors in Alzheimer's disease. BRAIN PATHOLOGY 10: 796

Arendt, T, Stieler, J, Strijkstra, AM, Hut, RA, Rudiger, J, Van der Zee, EA, Harkany, T, Holzer, M, Hartig, W (2003) Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals. JOURNAL OF NEUROSCIENCE 23: 6972-6981

Arevalo-Rodriguez, M, Cardenas, ME, Wu, XY, Hanes, SD and Heitman, J (2000) Cyclophilin A and Ess1 interact with and regulate silencing by the Sin3-Rpd3 histone deacetylase. EMBO JOURNAL 19: 3739-3749

Arima K; Izumiyama Y; Nakamura M; Nakayama H; Kimura M; Ando S; Ikeda K; Takahashi K. (1998) Argyrophilic tau-positive twisted and non-twisted tubules in astrocytic processes in brains of Alzheimer-type dementia: an electron  microscopical study. Acta Neuropathol (Berl), 95:1, 28-39

Arima_K, Nakamura_M, Sunohara_N, Nishio_T, Ogawa_M, Hirai_S, Kawai_M, Ikeda_K. (1999) Immunohistochemical and ultrastructural characterization of  neuritic clusters around ghost tangles in the hippocampal formation in progressive supranuclear palsy brains. ACTA NEUROPATHOLOGICA, 1999, Vol.97, No.6, pp.565-576

Armogida M, Petit A, Vincent B, ScarzelloS, Alves da Costa C, Checler F (2001) Endogenous b-amyloid production in presenilin-deficient embryonic mouse fibroblasts. NATURE CELL BIOLOGY 3: 1030-1033

Armstrong, RA (2000) Diffuse beta-amyloid (A beta) deposits and neurons: in situ secretion or diffusion of A beta? ALZHEIMERS REPORTS 3: 289-294

Armstrong, RA (2003) Quantifying the pathology of neurodegenerative disorders: quantitative measurements, sampling strategies and data analysis. HISTOPATHOLOGY 42: 521-529

Armstrong_RA, Cairns_NJ, Lantos_PL (1998) Lewy body and Alzheimer pathology in temporal lobe in dementia with Lewy bodies. ALZHEIMERS REPORTS 1: 159-163

Armstrong_RA, Cairns_NJ, Lantos_PL (1999)  Laminar distribution of Pick bodies, Pick cells and Alzheimer disease pathology in the frontal and temporal cortex in Pick's disease. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 25: 266-271

Armstrong, RA, Cairns, NJ and Lantos, PL (2001a) What does the study of the spatial patterns of pathological lesions tell us about the pathogenesis of neurodegenerative disorders? NEUROPATHOLOGY 21: 1-12

Armstrong, RA, Cairns, NJ and Lantos, PL (2001b) Spatial pattern of prion protein deposits in patients with sporadic Creutzfeldt-Jakob disease. NEUROPATHOLOGY 21: 19-24

Armstrong, RA, Lantos, PL, Cairns, NJ (2005) Overlap between neurodegenerative disorders. NEUROPATHOLOGY 25: 111-124

Arriagada, P.V., Growdon, J.H., Hedley-Whyte, E.T. and Hyman, B.T. (1992) Neurofibrillary tangles but not senile plaques parrallel duration and severity of Alzheimer's disease. Neurology 42: 631-639

Atamna, H (2004) Heme, iron, and the mitochondrial decay of ageing. AGEING RESEARCH REVIEWS 3: 303-318

Atchison, FW, Capel, B, Means, AR (2003) Pin1 regulates the timing of mammalian primordial germ cell proliferation. DEVELOPMENT 130: 3579-3586  

Atchison, FW, Means, AR (2003) Spermatogonial depletion in adult Pin1-deficient mice. BIOLOGY OF REPRODUCTION 69: 1989-1997

Atchison, FW, Means, AR (2004) A role for Pin1 in mammalian germ cell development and spermatogenesis. FRONTIERS IN BIOSCIENCE 9: 3248-3256

Athan, ES, Williamson, J, Ciappa, A, Santana, V, Romas, SN, Lee, JH, Rondon, H, Lantigua, RA, Medrano, M, Torres, M, Arawaka, S, Rogaeva, E, Song, YQ, Sato, C, Kawarai, T, Fafel, KC, Boss, MA, Seltzer, WK, Stern, Y, St George-Hyslop, P, Tycko, B, Mayeux, R (2001) A founder mutation in presenilin 1 causing early-onset Alzheimer disease in unrelated Caribbean Hispanic families. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 286: 2257-2263

Athlan_ES, Sacher_MG, Mushynski_WE. (1997) Associations between intermediate filament proteins expressed in cultured dorsal root ganglion neurons. JOURNAL OF NEUROSCIENCE RESEARCH, 1997, Vol.47, No.3, pp.300-310

Atzori, C, Ghetti, B, Piva, R, Srinivasan, AN, Zolo, P, Delisle, MB, Mirra, SS, Migheli, A (2001) Activation of the JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 60: 1190-1197

Augustinack, JC, Sanders, JL, Tsai, LH, Hyman, BT (2002) Colocalization and fluorescence resonance energy transfer between cdk5 and AT8 suggests a close association in pre-neurofibrillary tangles and neurofibrillary tangles. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 61: 557-564

Augustinack, JC, Schneider, A, Mandelkow, EM, Hyman, BT (2002) Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease. ACTA NEUROPATHOLOGICA 103: 26-35 

Avila, J, Lim, F, Moreno, F, Belmonte, C, Cuello, AC (2002) Tau function and dysfunction in neurons - Its role in neurodegenerative disorders. MOLECULAR NEUROBIOLOGY 25: 213-231

Avila, J, Lucas, JL, Perez, M, Hernandez, F (2004) Role of tau protein in both physiological and pathological conditions. PHYSIOLOGICAL REVIEWS 84: 361-384  

Avila, J, Perez, M, Lim, F, Gomez-Ramos, A, Hernandez, F, Lucas, JJ (2004) Tau in neurodegenerative diseases: Tau phosphorylation and assembly. NEUROTOXICITY RESEARCH 6: 477-482

Ayala, G, Wang, DG, Wulf, G, Frolov, A, Li, R, Sowadski, J, Wheeler, TM, Lu, KP, Bao, L (2003) The prolyl isomerase Pin1 is a novel prognostic marker in human prostate cancer. CANCER RESEARCH 63: 6244-6251
 
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Baekelandt, V, Moechars, D, Laenen, I, Lorent, K and Van Leuven, F (1999) Disturbance of the glutamatergic system in mice transgenic for the amyloid precursor protein. ALZHEIMERS REPORTS 2: 359-368

Bajo, M, Yoo, BC, Cairns, N, Gratzer, M, Lubec, G (2001) Neurofilament proteins NF-L, NF-M and NF-H in brain of patients with Down syndrome and Alzheimer's disease. AMINO ACIDS 21: 293-301

Baki, L, Marambaud, P, Efthimiopoulos, S, Georgakopoulos, A, Wen, P, Cui, W, Shioi, J, Koo, E, Ozawa, M, Friedrich, VL and Robakis, NK (2001) Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 98: 2381-2386

Baloyannis, SJ (2005) Morphological and morphometric alterations of Cajal-Retzius cells in early cases of Alzheimer's disease: A Golgi and electron microscope study. INTERNATIONAL JOURNAL OF NEUROSCIENCE 115: 965-980

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