Literature: A-K ; L-Z ; subject area
Compiled by: Julian Thorpe
The Tauopathies
N.B. This aspect of our research is funded by a 3-Year Project Grant from
***** (See the University Press Release about our Grant) *****
 | The tauopathies are a group of diverse dementias and movement
disorders which have as a common pathological feature
the presence of intracellular accumulations
of abnormal filaments of tau protein
. |
| Pin1 protein is therefore likely to have a role in
these diseases , not only because of the presence of
tangles, but also - as in
AD
- the re-expression and activation
of cell cycle-related proteins has
also been found in the tauopathies
Down's Syndrome
(DS), Corticobasal Degeneration
(CBD), Frontotemporal
Dementia with Parkinsonism linked to Chromosome 17
(FTDP17), Pick's Disease (PiD) and
Progressive Supranuclear Palsy (PSP; Husseman et al., 2000). |
| I would suggest seeing Lee, Goedert and Trojanowski's 2001 review article as a good starting point in getting 'up to speed' on these tauopathies. |
(These journals include: Neurology, Neurobiology of Disease, Journal of Neurochemistry, Alzheimer's Disease Review)
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Allen, B, Ingram, E, Takao, M, Smith, MJ, Jakes, R,
Virdee, K, Yoshida, H, Holzer, M, Craxton, M, Emson, PC, Atzori, C, Migheli, A,
Crowther, RA, Ghetti, B, Spillantini, MG, Goedert, M (2002) Abundant tau filaments and nonapoptotic
neurodegeneration in transgenic mice expressing human P301S tau protein
Arai, T, Ikeda, K, Akiyama, H, Tsuchiya, K, Iritani, S, Ishiguro, K, Yagishita, S, Oda, T, Odawara, T, Iseki, E (2003) Different immunoreactivities of the microtubule-binding region of tau and its molecular basis in brains from patients with Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration. ACTA NEUROPATHOLOGICA 105: 489-498
Arai, T, Nonaka, T, Hasegawa, M, Akiyama, H, Yoshida,
M, Hashizume, Y, Tsuchiya, K, Oda, T, Ikeda, K (2003)
Neuronal and glial inclusions in frontotemporal dementia with or without motor
neuron disease are immunopositive for p62. NEUROSCIENCE LETTERS 342: 41-44
Armstrong, RA, Lantos, PL, Cairns, NJ (2005) Overlap between neurodegenerative disorders. NEUROPATHOLOGY 25: 111-124
Avila, J, Lim, F, Moreno, F, Belmonte, C, Cuello, AC (2002) Tau function and dysfunction in neurons - Its role in neurodegenerative disorders. MOLECULAR NEUROBIOLOGY 25: 213-231
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Russo, C, Schettini, G, Pagano, SF, Parati, EA, Mazzoli, F, Nicosia, F,
Signorini, S, Feudatari, E, Binetti, G (2003)
BACE-2 is overexpressed in Down's syndrome. EXPERIMENTAL NEUROLOGY 182: 335-345
Bendiske, J, Caba, E, Brown, QB, Bahr, BA (2002) Intracellular deposition, microtubule destabilization, and transport failure: An "early" pathogenic cascade leading to synaptic decline. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 61: 640-650
Berry, RW, Abraha, A, Lagalwar, S, LaPointe, N, Gamblin,
TC, Cryns, VL, Binder, LI (2003)
Inhibition of tau polymerization by its carboxy-terminal caspase cleavage
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Berry, RW, Sweet, AP, Clark, FA, Lagalwar, S, Lapin, BR, Wang, T, Topgi, S, Guillozet-Bongaarts, AL, Cochran, EJ, Bigio, EH, Binder, LI (2004) Tau epitope display in progressive supranuclear palsy and corticobasal degeneration. JOURNAL OF NEUROCYTOLOGY 33: 287-295
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A (2003) Frontotemporal and motor neurone degeneration with neurofilament
inclusion bodies: additional evidence for overlap between FTD and ALS.
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Bird, T, Knopman, D, VanSwieten, J, Rosso, S, Feldman,
H, Tanabe, H, Graff-Raford, N, Geschwind, D, Verpillat, P, Hutton, M (2003)
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NEUROLOGY 54: S29-S31
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B, Robinson, C, Macaulay, R, George, D (2002) Progressive supranuclear palsy diagnosis and
confounding features: Report on 16 autopsied cases
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Boeve, B, Dickson, D, Duffy, J, Bartleson, J, Trenerry, M, Petersen, R (2003) Progressive nonfluent aphasia and subsequent aphasic dementia associated with atypical progressive supranuclear palsy pathology. EUROPEAN NEUROLOGY 49: 72-78
Borghi, R, Piccini, A, Delacourte, A, Strocchi, P, Zaccheo, D, Tabaton, M (2004) Protein levels of glycogen synthase 3 kinase are normal in progressive supranuclear palsy. NEUROSCIENCE LETTERS 366: 67-70
Bornebroek, M, Breteler, MMB (2004) Epidemiology of non-AD dementias. CLINICAL NEUROSCIENCE RESEARCH 3: 349-361
Brandt, R, Hundelt, M, Shahani, N (2005) Tau alteration and neuronal degeneration in tauopathies: mechanisms and models. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1739: 331-354
Broe, M, Hodges, JR, Schofield, E, Shepherd, CE, Kril,
JJ, Halliday, GM (2003) Staging disease severity in pathologically
confirmed cases of frontotemporal dementia. NEUROLOGY 60: 1005-1011
Buee, L, Delacourte, A (2002) Alzheimer's disease: just another tauopathy? MEDECINE SCIENCES 18: 727-736
Burn,
DJ, Lee, AJ (2002)
Cairns, NJ, Brannstrom, T, Khan, MN, Rossor, MN, Lantos, PL (2003) Neuronal loss in familial frontotemporal dementia with ubiquitin-positive, tau-negative inclusions. EXPERIMENTAL NEUROLOGY 181: 319-326
Campdelacreu, J, Ezquerra, M, Munoz, E, Oliva, R,
Tolosa, E (2003) Mutational study of the nuclear factor kappa B
inducing kinase gene in patients with progressive supranuclear palsy.
NEUROSCIENCE LETTERS 340: 158-160
Carrilho, PEM, Barbosa, ER (2002) Progressive supranuclear palsy in a sample of Brazilian population - Clinical features of 16 patients. ARQUIVOS DE NEURO-PSIQUIATRIA 60: 917-922
Cash, AD, Aliev, G, Siedlak, SL, Nunomura, A, Fujioka,
H, Zhu, XW, Raina, AK, Vinters, HV, Tabaton, M, Johnson, AB, Paula-Barbosa, M,
Avila, J, Jones, PK, Castellani, RJ, Smith, MA, Perry, G (2003)
Microtubule reduction in Alzheimer's disease and aging is independent of tau
filament formation. AMERICAN JOURNAL OF PATHOLOGY 162: 1623-1627
Cataldo, AM, Petanceska, S, Peterhoff, CM, Terio, NB,
Epstein, CJ, Villar, A, Carlson, EJ, Staufenbiel, M, Nixon, RA (2003)
App gene dosage modulates endosomal abnormalities of Alzheimer's disease in a
segmental trisomy 16 mouse model of Down syndrome. JOURNAL OF NEUROSCIENCE 23:
6788-6792
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Chang, HT, Cortez, S, Vonsattel, JP, Stopa, EG, Schelper, RL (2004) Familial frontotemporal dementia: a report of three cases of severe cerebral atrophy with rare inclusions that are negative for tau and synuclein, but positive for ubiquitin. ACTA NEUROPATHOLOGICA 108: 10-16
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Chirichigno,
JW, Manfredi, G, Beal, MF, Albers, DS (2002)
Chiti, F, Stefani, M, Taddei, N, Ramponi, G, Dobson, CM
(2003) Rationalization of the effects of mutations on peptide
and protein aggregation rates. NATURE 424: 805-808
Chow, TW, Miller, BL, Boone, K, Mishkin, F, Cummings, JL (2002) Frontotemporal dementia classification and neuropsychiatry. NEUROLOGIST 8: 263-269
Colosimo, C, Osaki, Y, Vanacore, N, Lees, AJ (2003)
Lack of association between progressive supranuclear palsy and arterial
hypertension: A clinicopathological study. MOVEMENT DISORDERS 18: 694-697
Connell, JW, Rodriguez-Martin, T, Gibb, GM, Kahn, NM, Grierson, AJ, Hanger, DP, Revesz, T, Lantos, PL, Anderton, BH, Gallo, JM (2005) Quantitative analysis of tau isoform transcripts in sporadic tauopathies. MOLECULAR BRAIN RESEARCH 137: 104-109
Curcio, SAM, Kawarai, T, Paterson, AD, Maletta, RG, Puccio, G, Perri, M, Di Natale, M, Palermo, S, Foncin, JF, Hyslop, PHS, Bruni, AC (2002) A large Calabrian kindred segregating frontotemporal dementia. JOURNAL OF NEUROLOGY 249: 911-922
Davidsson, P, Sjogren, M, Andreasen, N, Lindbjer, M, Nilsson, CL, Westman-Brinkmalm, A, Blennow, K (2002) Studies of the pathophysiological mechanisms in frontotemporal dementia by proteome analysis of CSF proteins. MOLECULAR BRAIN RESEARCH 109: 128-133
de
Mendonca, A, Ribeiro, F, Guerreiro, M, Garcia, C (2004) Frontotemporal
Mild Cognitive Impairment. JOURNAL OF ALZHEIMERS DISEASE 6: 1-9
de Silva, R, Hardy, J, Crook, J, Khan, N, Graham, EA,
Morris, CM, Wood, NW, Lees, AJ (2002) The tau locus is not significantly associated with
pathologically confirmed sporadic Parkinson's disease
de Silva, R, Lashley, T, Gibb, G, Hanger, D, Hope, A,
Reid, A, Bandopadhyay, R, Utton, M, Strand, C, Jowett, T, Khan, N, Anderton, B,
Wood, N, Holton, J, Revesz, T, Lees, A (2003)
Pathological inclusion bodies in tauopathies contain distinct complements of tau
with three or four microtubule-binding repeat domains as demonstrated by new
specific monoclonal antibodies. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 29:
288-302
DeTure, M, Ko, LW, Easson, C, Yen, SH (2002)
tau assembly in inducible transfectants expressing
wild-type or FTDP-17 tau
Dickson,
DW, Bergeron, C, Chin, SS, Duyckaerts, C, Horoupian, D, Ikeda, K, Jellinger, K,
Lantos, PL, Lippa, CF, Mirra, SS, Tabaton, M, Vonsattel, JP, Wakabayashi, K,
Litvan, I (2002)
D'Souza, I, Schellenberg, GD (2002) Tau exon 10 expression involves a bipartite intron 10 regulatory sequence and weak 5' and 3 ' splice sites. JOURNAL OF BIOLOGICAL CHEMISTRY 277: 26587-26599
D'Souza, I, Schellenberg, GD (2005) Regulation of tau isoform expression and dementia. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1739: 104-115
Ermak, G, Davies, KJA (2003) DSCR1(Adapt78) - A Janus gene providing stress protection but causing Alzheimer's disease? IUBMB LIFE 55: 29-31
Faltraco, F, Teipel, SJ, Blennow, K, Moller, HJ, Hampel,
H (2003) A new polymorphism in the cell division cycle 2 gene
is associated with Alzheimer's disease and frontotemporal dementia.
PHARMACOPSYCHIATRY 36: 72
Ferman, TJ, McRae, CA, Arvanitakis, Z, Tsuboi, Y, Vo,
A, Wszolek, ZK (2003) Early and pre-symptomatic neuropsychological
dysfunction in the PPND family with the N279K tau mutation. PARKINSONISM &
RELATED DISORDERS 9: 265-270
Ferrer, I (2004) Stress kinases involved in tau phosphorylation in Alzheimer's disease, tauopathies and APP transgenic mice. NEUROTOXICITY RESEARCH 6: 469-475
Ferrer, I, Barrachina, M, Puig, B (2002) Glycogen synthase kinase-3 is associated with neuronal
and glial hyperphosphorylated tau deposits in Alzheimer's disease, Pick's
disease, progressive supranuclear palsy and corticobasal degeneration
Ferrer, I, Barrachina, M, Puig, B (2002) Anti-tau phospho-specific Ser(262) antibody recognizes
a variety of abnormal hyperphosphorylated tau deposits in tauopathies including
Pick bodies and argyrophilic grains
Ferrer, I, Barrachina, M, Tolnay, M, Rey, MJ, Vidal, N,
Carmona, M, Blanco, R, Puig, B (2003)
Phosphorylated protein kinases associated with neuronal and glial tau deposits
in argyrophilic grain disease. BRAIN PATHOLOGY 13: 62-78
Ferrer, I, Pastor, P, Rey, MJ, Munoz, E, Puig, B, Pastor, E, Oliva, R, Tolosa, E (2003) Tau phosphorylation and kinase activation in familial tauopathy linked to deln296 mutation. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 29: 23-34
Gamblin, TC, Berry, RW, Binder, LI (2003) Tau polymerization: Role of the amino terminus. BIOCHEMISTRY 42: 2252-2257
Giasson, BI, Sampathu, DM, Wilson, CA,
Vogelsberg-Ragaglia, V, Mushynski, WE, Lee, VMY (2002)
The environmental toxin arsenite induces tau hyperphosphorylation
Gislason, TB, Sjogren, M, Larsson, L, Skoog, I (2003)
The prevalence of frontal variant frontotemporal dementia and the frontal lobe
syndrome in a population based sample of 85 year olds. JOURNAL OF NEUROLOGY
NEUROSURGERY AND PSYCHIATRY 74: 867-871
Goedert, M, Jakes, R (2005) Mutations causing neurodegenerative tauopathies. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE 1739: 240-250
Goetz, CG (2003)
Progressive supranucleare palsy. REVUE NEUROLOGIQUE 159: S25-S29
Goetz, CG, Leurgans, S, Lang, AE, Litvan, I (2003)
Progression of gait, speech and swallowing deficits in progressive supranuclear
palsy. NEUROLOGY 60: 917-922
Graham, NL, Bak, TH, Hodges, JR (2003)
Corticobasal degeneration as a cognitive disorder. MOVEMENT DISORDERS 18:
1224-1232
Granholm, ACE, Ford, KA, Hyde, LA, Bimonte, HA, Hunter,
CL, Nelson, M, Albeck, D, Sanders, LA, Mufson, EJ, Crnic, LS (2002) Estrogen restores cognition and cholinergic phenotype
in an animal model of Down syndrome
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Greber-Platzer, S, Fleischmann, C, Nussbaumer, C, Cairns, N, Lubec, G (2003) Increased RNA levels of the 25 kDa synaptosomal associated protein in brain samples of adult patients with Down Syndrome. NEUROSCIENCE LETTERS 336: 77-80
Grover, A, England, E, Baker, M, Sahara, N, Adamson, J,
Granger, B, Houlden, H, Passant, U, Yen, SH, DeTure, M, Hutton, M (2003)
A novel tau mutation in exon 9 (1260V) causes a four-repeat tauopathy.
EXPERIMENTAL NEUROLOGY 184: 131-140
Gydesen, S, Brown, JM, Brun, A, Chakrabarti, L, Gade,
A, Johannsen, P, Rossor, M, Thusgaard, T, Grove, A, Yancopoulou, D, Spillantini,
MG, Fisher, EMC, Collinge, J, Sorensen, SA (2002) Chromosome 3 linked frontotemporal dementia (FTD-3)
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Hamilton, RL (2003)
The other dementias: The neuropathology of the non-Alzheimer's disease
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Hanger, DP, Gibb, GM, de Silva, R, Boutajangout, A,
Brion, JP, Revesz, T, Lees, AJ, Anderton, BH (2002) The complex relationship between soluble and insoluble
tau in tauopathies revealed by efficient dephosphorylation and specific
antibodies
Hartzler, AW, Zhu, XW, Siedlak, SL, Castellani, RJ,
Avila, J, Perry, G, Smith, MA (2002) The p38 pathway is activated in Pick disease and
progressive supranuclear palsy: a mechanistic link between mitogenic pathways,
oxidative stress, and tau
Hattori, M, Hashizume, Y, Yoshida, M, Iwasaki, Y,
Hishikawa, N, Ueda, R, Ojika, K (2003)
Distribution of astrocytic plaques in the corticobasal degeneration brain and
comparison with tuft-shaped astrocytes in the progressive supranuclear palsy
brain. ACTA NEUROPATHOLOGICA 106: 143-149
Head, E, Lott, IT, Cribbs, DH, Cotman, CW, Rohn, TT
(2002) beta-amyloid deposition and neurofibrillary tangle
association with caspase activation in Down syndrome
Hernandez, F, Perez, M, Lucas, JJ, Mata, AM, Bhat, R, Avila, J (2004) Glycogen synthase kinase-3 plays a crucial role in tau exon 10 splicing and intranuclear distribution of SC35 - Implications for Alzheimer's disease. JOURNAL OF BIOLOGICAL CHEMISTRY 279: 3801-3806
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Tau and axonopathy in neurodegenerative disorders
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Lee,
EB, Skovronsky, DM, Abtahian, F, Doms, RW, Lee, VMY (2003) Secretion and intracellular generation of truncated A
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Lee, JI, Dhakal, BK, Lee, J, Bandyopadhyay, J, Jeong, SY, Eom, SH, Kim, DH, Ahnn, J (2003) The Caenorhabditis elegans homologue of down syndrome critical region 1, RCN-1, inhibits multiple functions of the phosphatase calcineurin. JOURNAL OF MOLECULAR BIOLOGY 328: 147-156
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